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Technology Raman spectroscopy portable device: Truscan
 
Protection strategy Product authentication
Type Analytical technique
System Laboratory based
Medium Medicine : pills, bulk product, liquid
Authentication/Identificaton Authentication
Traceability No
Cost dozens of thousands of USD
Required equipment The device
Vertification level Authorities with the adequate equipment;
Laboratories
N.B. Truscan
Description Portable device capable of analyzing raw materials such as medicine and provide a spectrum representative of the molecular composition of the product. This spectrum is then compared with the spectrum of the medicine’s correct chemical combination stored in the device. If the two spectrum present significant dissimilarities the device will declare the product tested as fake.
 
Strengths Objective analysis of the product (contents analysis);
Can be done without removing the primary pack in most cases (through blister pack if it is transparent, through plastic bag, through glass);
Relatively easy to use;
Portable;
Fast;
The device can be connected to a computer to download the spectrum in PDF or in an Excel format;
 
Limitations Requires specific equipment: the device and some training for the person who is manipulating the device;
Methods and reference spectra need to be implemented for specific products, laboratories generally do not divulge those information to authorities;
Cost;
The medicine needs to contain more than 10% of API to be detected correctly;
Titanium oxide, cellulose and its derivatives on coated pills produce fluorescence and therefore interfere with Raman signals;
 
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